All Protocols and Video Articles for scientific research | JoVE

Showing 13 - 24 of 164 videos for "INDEL"

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Journal (Biology)

Scalable Transfection of Maize Mesophyll Protoplasts

Jackson Tonnies, Nicholas A. Mueth, Sayeh Gorjifard, Jonah Chu, Christine Queitsch

¹Genome Sciences Department,University of Washington

Journal (Biology)

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연구 방법 컬렉션

Efficient PAM-Less Base Editing for Zebrafish Modeling of Human Genetic Disease with zSpRY-ABE8e

Shaohui Zheng², Fang Liang, Yu Zhang², Ji-Feng Fei, Wei Qin², Yanmei Liu²

¹Key Laboratory of Brain, Cognition and Education Science,Ministry of Education, ²Institute for Brain Research and Rehabilitation, Guangdong Key Laboratory of Mental Health and Cognitive Science,South China Normal University, ³Institute of Modern Aquaculture Science and Engineering, Guangdong Provincial Engineering Technology Research Center for Environmentally Friendly Aquaculture, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Sciences,South China Normal University, ⁴Department of Pathology, Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences

Journal (Genetics)

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연구 방법 컬렉션

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration

Michael Landowski², Samuel Grindel, Ying Hao, Sakae Ikeda², Catherine Bowes Rickman⁴, Akihiro Ikeda²

¹Department of Medical Genetics,University of Wisconsin-Madison, ²McPherson Eye Research Institute,University of Wisconsin-Madison, ³Department of Ophthalmology,Duke University, ⁴Department of Cell Biology,Duke University

Journal (Biology)

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연구 방법 컬렉션

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Michael Finnegan, Jeanne Hamet, Erick Desmarais, Stéphanie Bedhomme

¹CEFE,University of Montpellier, CNRS, EPHE, IRD, Montpellier, France, ²ISEM,University of Montpellier, CNRS, EPHE, IRD, Montpellier, France

Journal (Genetics)

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연구 방법 컬렉션

Screening Sperm for the Rapid Isolation of Germline Edits in Zebrafish

Brittney Voigt, Ryoko Minowa, Ryan S. Gray²

¹Department of Molecular Biosciences,The University of Texas at Austin, ²Department of Nutritional Sciences,The University of Texas at Austin

Journal (Cancer Research)

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells

Tommaso Sconocchia, Johannes Foßelteder, Thomas Köhnke, Ravindra Majeti, Andreas Reinisch³

¹Division of Hematology, Department of Internal Medicine,Medical University of Graz, ²Division of Hematology, Stanford Cancer Institute, Stanford Institute for Stem Cell Biology and Regenerative Medicine,Stanford University School of Medicine, ³Department of Blood Group Serology and Transfusion Medicine,Medical University of Graz

Journal (Developmental Biology)

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연구 방법 컬렉션

CRISPR/Cas9-Mediated Highly Efficient Gene Targeting in Embryonic Stem Cells for Developing Gene-Manipulated Mouse Models

Manabu Ozawa*¹, Chihiro Emori*², Masahito Ikawa²

¹Laboratory of Reproductive Systems Biology, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science,The University of Tokyo, ²Research Institute for Microbial Diseases,Osaka University

Journal (Medicine)

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연구 방법 컬렉션

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing

Pavel A. Nash, Pedro Silva-Pinheiro, Michal A. Minczuk

¹Medical Research Council Mitochondrial Biology Unit,University of Cambridge, Cambridge Biomedical Campus

Journal (Biology)

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연구 방법 컬렉션

The Isolation of Flowing Mesenteric Lymph in Mice to Quantify In Vivo Kinetics of Dietary Lipid Absorption and Chylomicron Secretion

Nikolaos L. Dedousis, Lihong Teng, Alison B. Kohan

¹Division of Endocrinology and Metabolism, Department of Medicine, School of Medicine,University of Pittsburgh

Journal (Developmental Biology)

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연구 방법 컬렉션

Efficient Genome Editing of Mice by CRISPR Electroporation of Zygotes

Chantal K. Diallo, Andrew J. Modzelewski

¹Department of Biomedical Sciences, School of Veterinary Medicine,The University of Pennsylvania

Journal (Bioengineering)

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연구 방법 컬렉션

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

Marcos Ezequiel Gramajo*¹, Ryan J. Lake*², Yi Lu, Ana Sol Peinetti

¹INQUIMAE (CONICET), Departamento de Química Inorgánica, Analítica y Química Física, Facultad de Ciencias Exactas y Naturales,Universidad de Buenos Aires, ²Department of Chemistry,University of Illinois at Urbana-Champaign, ³Department of Chemistry,University of Texas at Austin

Journal (Engineering)

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연구 방법 컬렉션

Co-localizing Kelvin Probe Force Microscopy with Other Microscopies and Spectroscopies: Selected Applications in Corrosion Characterization of Alloys

Olivia O. Maryon*¹, Corey M. Efaw*¹, Frank W. DelRio, Elton Graugnard³, Michael F. Hurley³, Paul H. Davis³

¹Micron School of Materials Science & Engineering,Boise State University, ²Material, Physical, and Chemical Sciences Center,Sandia National Laboratories, ³Center for Advanced Energy Studies

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