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Stereotactic Intrakraniell Implantasjon og<em> In vivo</em> Bioluminescent Imaging av tumorxenotransplantater i en mus modell System of glioblastoma multiforme
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JoVE Journal Medicine
Stereotactic Intracranial Implantation and In vivo Bioluminescent Imaging of Tumor Xenografts in a Mouse Model System of Glioblastoma Multiforme

Stereotactic Intrakraniell Implantasjon og<em> In vivo</em> Bioluminescent Imaging av tumorxenotransplantater i en mus modell System of glioblastoma multiforme

DOI:
10.3791/4089-v

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10:52 min

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September 25, 2012

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, , , ,
1Department of Radiation Oncology,University of Pennsylvania

Chapters

  • 00:05Title
  • 02:08Orthotopic Xenograft Implantation
  • 07:41Bioluminescent Imaging (BLI) to Monitor Tumor Growth and Response to Therapy
  • 08:38Results: In Vivo Bioluminescent Imaging of Tumor Xenografts in a Mouse Model System of Glioblastoma Multiforme
  • 09:52Conclusion

Summary

Automatic Translation

Automatic Translation

Vi beskriver en integrert metode for den presise, stereotactic Implantering av humant glioblastoma multiforme celler i hjernen på nakne mus og etterfølgende serienummer<em> In vivo</em> Imaging å overvåke vekst og respons på behandling av de resulterende xenografter.

Tags

Stereotactic Intracranial ImplantationIn Vivo Bioluminescent ImagingTumor XenograftsMouse Model SystemGlioblastoma MultiformeHigh-grade Primary Brain CancerMedian SurvivalStandard Tri-modality TreatmentSurgical ResectionRadiation TherapyTemozolomide ChemotherapyTherapeutic ApproachesAnimal ModelsTumor GrowthTreatment ResponseBio-imageable GBM Cancer CellsNude MiceAnatomic LocationsIn Vivo Bioluminescent ImagingIntracranial Xenograft GrowthPerioperative MorbidityMortality

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