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的简便和环保路线制造聚乳酸支架与分级孔径
JoVE 신문
생체공학
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JoVE 신문 생체공학
A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size
DOI:

13:46 min

October 17, 2016

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Chapters

  • 00:00Title
  • 01:43Sodium Chloride Grinding and Sieving
  • 02:30Preliminary Mixing of the Materials
  • 03:36Compression Molding I (Monolayers)
  • 04:56Compression Molding II (Three-layers)
  • 05:59Leaching and Drying
  • 06:27Porosity Evaluation
  • 07:00Broken Scaffold in Liquid Nitrogen
  • 07:14Fixing Scaffold on Aluminum Stubs
  • 07:25Compressive Tests
  • 07:44Tensile Tests
  • 07:56Results: SEM Analysis
  • 11:34Results: Comprehensive Tests
  • 12:09Results: Tensile Tests
  • 12:38Conclusion

Summary

자동 번역

In this work, poly(lactic acid)/polyethylene glycol (PLA/PEG) scaffolds were prepared by using a combination of melt mixing and selective leaching. The method herein discussed permitted to develop three-layer scaffolds by highly controlling both porosity and pore size. The mechanical properties were also evaluated in a physiological environment.

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