Journal
/
생물학
/
Transverse Aortic Constriction in Mice
JoVE 신문
생물학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 생물학
Transverse Aortic Constriction in Mice

Transverse Aortic Constriction in Mice

DOI:
10.3791/1729-v

•

08:25 min

•

April 21, 2010

•

, ,
1Department of Molecular Physiology and Biophysics,Baylor College of Medicine (BCM), 2The Margaret M. and Albert B. Alkek Department of Medicine,Baylor College of Medicine (BCM)

Chapters

  • 00:00Title
  • 00:42Introduction
  • 01:10Preparing the Operating Field
  • 02:02Preparing and Intubation of Mice
  • 03:25Ligation of the Transverse Aorta
  • 06:31Confirmation of Successful Ligation of the Transverse Aorta
  • 07:32Results of a Successful Transverse Aortic Constriction
  • 08:02Conclusion

Summary

자동 번역

자동 번역

Transverse aortic constriction (TAC) in the mouse is a commonly used experimental model to study mechanisms underlying cardiac hypertrophy and heart failure development. Here, we describe procedures to constrict the aorta to create a reproducible degree of cardiac hypertrophy in mice.

Tags

Transverse Aortic ConstrictionTACPressure OverloadCardiac HypertrophyHeart FailureMurine TAC ModelCardiovascular DiseasesSignaling ProcessesLeft Anterior Descending Coronary Artery OcclusionReproducible ModelGradual Time CourseSurgical ProcedureHigh Frequency Doppler ProbeBlood Flow VelocitiesLeft Ventricular Hypertrophy

Article

Embed

플레이리스트에 추가

Usage Statistics

Related Videos

check_url/kr/1729?article_type=v

Heterotopic Heart Transplantation in Mice
check_url/kr/1729?article_type=v

Creation of Murine Experimental Abdominal Aortic Aneurysms with Elastase
check_url/kr/1729?article_type=v

Aortic Ring Assay
check_url/kr/1729?article_type=v

Isolation and Primary Culture of Mouse Aortic Endothelial Cells
check_url/kr/1729?article_type=v

Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells
check_url/kr/1729?article_type=v

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
check_url/kr/1729?article_type=v

Isolation and Culture of Primary Aortic Endothelial Cells from Miniature Pigs
check_url/kr/1729?article_type=v

Transverse Fracture of the Mouse Femur with Stabilizing Pin
check_url/kr/1729?article_type=v

Isolation of Primary Patient-specific Aortic Smooth Muscle Cells and Semiquantitative Real-time Contraction Measurements In Vitro
check_url/kr/1729?article_type=v

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

Read Article