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Chapters
- 00:05Title
- 01:13Introduction
- 01:44Syringe Preparation for Intraocular Injections
- 04:48Intraocular Injection Procedure: Targeting the Retina Globally
- 06:50Selectively Targeting Retinal Ganglion Cells from the Optic Nerve Stump
- 09:28RGC Targeting by Injection of the Transected Optic Nerve Stump
- 10:31Conclusion
Optic Nerve doorsnijding is een veel gebruikt model van de volwassen CNS verwonding. Dit model is ideaal voor het uitvoeren van een aantal experimentele manipulaties die het netvlies doel wereldwijd of direct de doelstelling van de gewonden neuronale populatie van retinale ganglioncellen.
Tags
Optic Nerve TransectionExperimental ManipulationsMammalian CNSRetinal Ganglion CellsOptic NerveAxotomizedApoptotic Neuronal Cell DeathVitreous ChamberDrug DeliveryIntraocular InjectionsViral VectorsPlasmidsSiRNAsAdeno-Associated Virus (AAV) VectorsRGCs TargetingSuperior ColliculusApoptotic Mechanisms
