Journal
/
/
Recapitulation of an Ion Channel IV Curve Using Frequency Components
JoVE 신문
생물학
This content is Free Access.
JoVE 신문 생물학
Recapitulation of an Ion Channel IV Curve Using Frequency Components
DOI:

10:14 min

February 08, 2011

,

Chapters

  • 00:05Title
  • 01:29Prepare Noise Function and Input Signal
  • 03:10Perform Voltage Clamp Measurements
  • 03:55Data Analysis – IV Curves, FFTs, and Correlation Coefficients
  • 05:16Results: Model Cell Recordings and IV-Frequency Curve Correlations
  • 08:51Future Application to Multiple Channels in Biological Cells
  • 09:33Conclusion

Summary

자동 번역

There are technical obstacles to measuring current flux through multiple ion channels simultaneously, and later discerning what portion of the transmembrane current is due to each channel type. To address this need, this method presents a way to generate the IV curve of individual channel types using specific frequency components.

Related Videos

Read Article