JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
Chapters
- 00:05Title
- 00:46Introduction
- 01:52Preparing the IL-1 System
- 02:42Ventilating a Mouse
- 03:34Perfusing a Ventilated Mouse
- 06:28Measuring Steady and Pulsatile Pulmonary Pressures and Flow
- 07:57Pulmonary Artery and Left Atrial Pressure Measurements
- 09:11Conclusion
El protocolo siguiente se describe el proceso de aislamiento, ventilación e instrumentación de los pulmones del ratón para medir constante o pulsátil vascular pulmonar de presión-flujo relaciones con el fin de cuantificar los efectos del flujo sanguíneo, el flujo de aire, los cambios en las vías respiratorias y los cambios vasculares en la poscarga del ventrículo derecho.
Tags
Isolated Mouse LungVentilated Mouse LungInstrumented Mouse LungPulsatile FlowPulmonary Vascular Pressure-flow RelationshipsPulmonary Arterial Flow RateFlow Rate WaveformAirway PressureLeft Atrial PressurePulmonary Vascular ResistanceMulti-point Pressure-flow CurvesPulmonary Vascular ImpedanceRight Ventricular AfterloadVascular CompliancePulmonary CirculationImpedance MetricsZero Hertz Impedance Z0Characteristic Impedance ZCIndex Of Wave Reflection RWDistal Arterial Cross-sectional AreaProximal Arterial StiffnessUpstream-downstream Impedance MismatchSympathetic Nervous System ToneVolume Status AnesthesiaPulmonary EmboliChronic HypoxiaVasoactive Agents
