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Journal / Bioengineering / Elastomeric PGS Scaffolds in Arterial Tissue…
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Bioengineering

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JoVE Journal Bioengineering
Elastomeric PGS Scaffolds in Arterial Tissue Engineering
 
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Elastomeric PGS Scaffolds in Arterial Tissue Engineering

Article DOI: 10.3791/2691-v • 08:35 min • April 8th, 2011
April 8th, 2011 •
1, 1,2
1Department of Bioengineering, University of Pittsburgh, 2McGowan Institute for Regenerative Medicine, University of Pittsburgh

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Elastomeric PGS scaffolds with vascular smooth muscle cells cultured in a pulsatile flow bioreactor may lead to promising small-diameter arterial constructs with native ECM production in a relatively short culture period.

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Elastomeric PGS Scaffolds Arterial Tissue Engineering Cardiovascular Disease Mortality Coronary Artery Disease Bypass Surgery Autologous Vessels Allografts Synthetic Grafts Inner Diameter Of Arteries Limited Applications Thrombotic Complications Compliance Mismatch Late Intimal Hyperplasia Tissue Engineering Small-diameter Arterial Constructs Nonthrombogenic Robust Compliant Tri-lamellar Structure Mechanical Properties Burst Pressure Collagen Production Elastin Production Compliance Graft Failure Elastomeric Biomaterial Mechanical Conditioning
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