Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

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DOI:

10.3791/2844-v

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13:21 min

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July 21, 2011

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Derek J. Averill*¹, Joel Garcia*¹, Buddhima N. Siriwardena-Mahanama*¹, Sashiprabha M. Vithanarachchi*¹, Matthew J. Allen

¹Department of Chemistry,Wayne State University

Chapters

00:05Title
01:20Metalation Using LnCl3 Salts
03:33Dialysis Workup
07:00Assessment of the Presence of Free Metal and Determination of Water-coordination Number (q)
09:50Relaxation Measurements
11:35Representative Results of Characterization
12:48Conclusion

Summary

자동 번역

We demonstrate the metalation, purification, and characterization of lanthanide complexes. The complexes described here can be conjugated to macromolecules to enable tracking of these molecules using magnetic resonance imaging.

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

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Chapters

Summary

자동 번역

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