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腔内中东大脑中动脉闭塞（MCAO）缺血性中风模型在小鼠体内的激光多普勒血流指导
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Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice
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腔内中东大脑中动脉闭塞（MCAO）缺血性中风模型在小鼠体内的激光多普勒血流指导

DOI:
10.3791/2879-v

•

13:01 min

•

May 08, 2011

•

, , , ,
1Department of Neurosurgery,University of Florida, 2Department of Anatomical Sciences,Shiraz University of Medical Sciences

Chapters

  • 00:05Title
  • 00:43Introduction
  • 01:57Suture Preparation
  • 02:40Animal Preparation
  • 04:19Koizumi’s Method
  • 06:04Reperfusion
  • 06:27Longa’s Method
  • 09:19Neurological Evaluation After MCAO
  • 09:26Score 1
  • 09:41Score 2
  • 09:50Score 3
  • 10:03Score 4
  • 10:12Staining and Quantitative Measurement of Brain Infarct Volume
  • 10:57Representative Results
  • 11:55Conclusion

Summary

자동 번역

자동 번역

腔内大脑中动脉闭塞（MCAO）模型是最常见的缺血性中风的实验模型中使用的模型。在这里，我们将展示在整个模型用激光多普勒血流计指南的细节，其代表性的成果。

Tags

Intraluminal Middle Cerebral Artery OcclusionMCAO ModelIschemic StrokeLaser Doppler Flowmetry GuidanceMiceThird Leading Cause Of DeathLeading Cause Of DisabilityCostUnited StatesRatModificationMolecular MechanismsBrain InjuryTherapeutic ModalitiesNoninvasive MethodTransgenic StrainsKnockout StrainsFocal Cerebral IschemiaIntraluminal SutureInternal Carotid ArteryBase Of The MCASpontaneous ReperfusionPermanent RetentionVideo DemonstrationDrawbacksPitfalls235-triphenyltetrazolium Chloride (TTC)Cerebral Infarction

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