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在小鼠永久性大脑中动脉结扎术中的应用

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The Application Of Permanent Middle Cerebral Artery Ligation in the Mouse

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在小鼠永久性大脑中动脉结扎术中的应用

DOI:

•

08:27 min

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July 25, 2011

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Gozde Colak, Anthony J. Filiano, Gail V.W. Johnson

¹Department of Pharmacology and Physiology,University of Rochester, ²Department of Neurology,University of Alabama at Birmingham, ³Departments of Anesthesiology, Pharmacology and Physiology,University of Rochester

Chapters

00:05Title
01:22Pre-surgical Preparation
03:25Surgical Procedure and MCA Ligation
05:29TTC Staining and Determination of Stroke Colume
06:06Directions to use ImageJ Software
07:26Representative Results
08:07Conclusion

Summary

자동 번역

大脑中动脉（MCA）结扎是一种技术，研究在动物模型局灶性脑缺血。在此方法中，通过开颅暴露大脑中动脉和烧灼结扎。此方法提供了高度重复性的脑梗死体积和增加手术后的生存率率比现有的其他方法。

Tags

Permanent MCA Ligation Focal Cerebral Ischemia Stroke Animal Models PMCAo Craniotomy Electrocoagulation Infarcts Cortical Regions Striatal Regions Neuroprotective Compounds Reproducible Infarcts Post-survival Rates MCA Artery

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