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1Department of Neuroscience and Cell Biology,University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 2Spinal Cord and Brain Injury Research Center, 3Department of Anatomy and Neurobiology, Department of Physical Medicine and Rehabilitation,University of Kentucky Chandler Medical Center
Chapters
- 00:05Title
- 01:23Craniectomy
- 05:46Induction of Injury
- 08:19Cognitive, Motor and Histological Outcomes
Lateral fluido percusión (LFP), un modelo establecido de lesión traumática del cerebro en ratones, se demostró. LFP cumple tres criterios principales para los modelos animales: relevancia validez, fiabilidad y clínicos. El procedimiento, que consiste en una craneotomía quirúrgica, la fijación del cubo seguida por la inducción de la lesión, lo que resulta en lesiones focales y difusas, que se describe es.
Tags
Lateral Fluid PercussionTraumatic Brain InjuryTBI ResearchHead InjuriesMorbidityMortalityPrimary InjurySecondary ConsequencesRegenerative ProcessesContusionSkull FractureShearingStretchingDisplacement Of BrainHematomasLacerationsVascular ResponseWhite Matter DamageDiffuse Axonal InjuryEdemaIncreased Intracranial PressureMicroscopic AlterationsExcitotoxic NeurotransmittersImmune MediatorsOxygen RadicalsLong-term Neurological DisabilitiesAnimal Models Of TBICellular EventsMolecular Events
