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Chapters
- 00:05Title
- 01:56Collecting Baseline von Frey Measurements Prior to Surgery
- 03:04Anesthesia and Preparation for Surgery
- 04:14Surgery
- 06:04Post-surgical Care and von Frey Measurements
- 06:37Results: von Frey Testing of 8-10 Week-old Mice Before and After Surgery
- 07:17Conclusion
Den skonas Nerve Injury djurmodell beskrivs här som en musmodell av perifer neuropatisk smärta efter partiell denervering av ischiasnerven som lesioning den sken-och gemensamma peroneusnerven grenar och lämnar de övriga Sural nerven intakt. Beteendemodifikation följd av mekanisk allodyni kvantifieras av von Frey filament.
Tags
Spared Nerve Injury (SNI) ModelPeripheral Neuropathic PainChronic Pain ConditionTrauma To Sensory NervesPeripheral Nervous SystemMechanical AllodyniaTactile StimuliSNI Mouse ModelLigation Of Sciatic Nerve BranchesTibial NerveCommon Peroneal NerveSural NerveHypersensitivity In Lateral Area Of PawControl SideVon Frey FilamentsBending ForcePain ReactionPaw WithdrawalFlinchingPaw LickingPain Threshold
