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Parasite Induced Genetisch Gedreven Auto Chagas hart-en vaatziekten in de Chicken Model
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Chapters
- 00:05Title
- 01:04Methods
- 04:35Results
- 08:22Conclusions
De inenting van<em> Trypanosoma cruzi</em> In vruchtbare eieren voor incubatie maakt de parasiet kDNA integratie minicircle in cellen van embryo's genoom. Kruisen toont de verticale verplaatsing van de mutaties nakomelingen. De kDNA integreert in coderende gebieden op verschillende chromosomen en de kippen sterven met een inflammatoire auto-hart-en vaatziekten.
Tags
Parasite-inducedGenetically-drivenAutoimmuneChagas Heart DiseaseChicken ModelTrypanosoma CruziAcute InfectionsChronic InfectionsChagas DiseaseAutoimmunityParasite PersistenceT. Cruzi InoculationAir ChamberFertilized EggsMature Chicken Immune SystemParasite-free At HatchingParasite Mitochondrial Kinetoplast DNA (kDNA) Minicircle IntegrationTargeted Prime TAIL-PCRSouthern HybridizationsCloningSequencingRuptured Open Reading FramesTranscription FactorsImmune System FactorsPhosphatase (GTPase)Adenylate CyclasePhosphorylases (PKCNF-Kappa B ActivatorPI-3K)MyocarditisRejection Of Target Heart FibersCytotoxic Lymphocytes
