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Chapters
- 00:05Title
- 02:11Growth of M. tuberculosis Biofilms for Drug Resistance
- 03:39Determining the Frequency of Drug Tolerant Persisters in M. tuberculosis Biofilms
- 06:39Culture Morphology and Drug Resistance
- 08:23Conclusion
Mycobacterium tuberculosis vormt drug tolerant biofilms wanneer gekweekt in bepaalde omstandigheden. Hier beschrijven werkwijzen voor het kweken M. tuberculose biofilms en het bepalen van de frequentie van de drug tolerante persisters. Deze protocollen zullen nuttig zijn voor verdere studies naar de mechanismen van tolerantie in M. tuberculose.
Tags
Mycobacterium TuberculosisGrowthBiofilmsStress ToleranceAntibioticsSurvivalMolecular MechanismsPathogenSelf-assemblingSurface AttachedMatrix Encapsulated StructuresBiofilm GrowthCommunitiesGenetic ComponentsSurface AttachmentIntercellular CommunicationsExtracellular Polymeric Substances (EPS)Environmental Stress TolerancePhysiological AdaptationBacilliComplex ArchitectureAnti-tuberculosis DrugsIsoniazidRifampicin
