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Chapters
- 00:05Title
- 01:31Chip Fabrication and Sample Pre-treatment
- 03:42Serum Fractionation
- 05:27MALDI-TOF Analysis of Peptides
- 06:40Data Analysis
- 08:36Results: iManipulation of MSP Thin Films for Selective Protein Enrichment
- 12:24Conclusion
Bu, insan serumu ile düşük molekül ağırlıklı proteinler ve peptitler selektif geri kazanımı için gözenekli silis ince film dayanan bir teknoloji geliştirilmiştir. Bizim gözenekli cips fiziko-kimyasal özellikleri ince peptid zenginleştirme önemli kontrolü sağlamak ve sonuçta tanısal amaçlı serum proteom profil ayarlı edildi.
Tags
Low Molecular Weight Protein EnrichmentMesoporous Silica Thin FilmsBiomarker DiscoveryCirculating BiomarkersEarly DiagnosisPrognosisTherapeutic EfficiencyLow Molecular Weight Proteome (LMWP)Mass Spectrometry (MS)Dynamic RangeProtein And Peptide ConcentrationsSample Pre-treatmentHighly Abundant ProteinsLow-abundance SpeciesProteomic-based ApproachesTwo-dimensional Polyacrylamide Gel-electrophoresis (2D-PAGE)Shotgun Proteomics MethodsClinical ApplicationsIsolation Of LMWP From BloodHigh Throughput ScreeningMulti-fractionation SystemMesoporous Silica Chips
