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Een<em> In vitro</em> Co-infectie model om te onderzoeken<em> Plasmodium falciparum</em>-HIV-1 Interacties in menselijke primaire monocyt-afgeleide immuuncellen
JoVE 신문
면역학 및 감염병학
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JoVE 신문 면역학 및 감염병학
An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells
DOI:

07:39 min

August 15, 2012

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Chapters

  • 00:05Title
  • 01:45Plasmodium falciparum-infected Red Blood Cell (iRBC) Purification
  • 02:35Exposure of Monocyte-derived Macrophages (MDM) to Plasmodium falciparum
  • 03:40Infection of MDM with a Fully Replicative HIV-1
  • 04:44Infection of MDM with Single Cycle Virus Encoding Luciferase
  • 05:56Results: Exposure of P. falciparum to MDM Decreases their Susceptibility to HIV-1 Infection
  • 07:16Conclusion

Summary

자동 번역

Wij hebben een<em> In vitro</em> Malaria-HIV-1 co-infectie model om de impact van de te bestuderen<em> Plasmodium falciparum</em> De HIV-1 replicatieve cyclus humane primaire monocyt-afgeleide macrofagen. Dit veelzijdige systeem gemakkelijk worden aangepast aan andere primaire celtypen gevoelig HIV-1-infectie.

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