JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
1Department of Pharmacology,Vanderbilt University, 2Vanderbilt Center for Bone Biology,Vanderbilt University, 3Department of Veterans Affairs,Tennessee Valley Healthcare System (VISN 9), 4Department of Medicine, Division of Clinical Pharmacology,Vanderbilt University, 5Department of Cancer Biology,Vanderbilt University
Chapters
- 00:05Title
- 01:22Cell Maintenance and Preparation
- 02:34Intracardiac Inoculation
- 04:26Intratibial Injection
- 06:57Representative Bone Metastasis Results
- 08:05Conclusion
Los modelos animales se utilizan con frecuencia para estudiar la metástasis del cáncer de hueso. En este protocolo vamos a describir dos métodos comunes de la inoculación del tumor para los estudios de metástasis óseas y describir brevemente algunos de los análisis utilizados para supervisar y cuantificar estos modelos.
Tags
Bone MetastasisMalignanciesBreast CancerProstate CancerLung CancerMolecular MechanismsTumor GrowthIn Vivo ModelsIntracardiac InoculationAthymic BalbC MicePC-3 Prostate CancerLung CarcinomaMouse Mammary Fat Pad TumorsMDA-MB-231 Breast Cancer ModelGFP ExpressionOsteotropismMetastasis To LungLiverAdrenal GlandsIntratibial InjectionsMammary Fat Pad Injections
