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探讨动脉平滑肌的KV7钾离子通道功能使用膜片钳电生理和压力Myography
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JoVE 신문 생물학
Exploring Arterial Smooth Muscle Kv7 Potassium Channel Function using Patch Clamp Electrophysiology and Pressure Myography
DOI:

11:02 min

September 14, 2012

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Chapters

  • 00:05Title
  • 02:08Dissection and Cleaning of Arteries
  • 03:04Cell Isolation for Patch Clamp Studies
  • 04:50Whole-cell Recording to Measure Kv7 Potassium Currents or Membrane Voltage
  • 06:36Use of Intact Artery Segments for Pressure Myography
  • 09:00Results: Kv7 Potassium Channel Function of Arterial Smooth Muscle using Patch Clamp Electrophysiology and Pressure Myography
  • 10:33Conclusion

Summary

자동 번역

测量KV7(KCNQ)钾离子通道活性的孤立动脉细胞(中与测量大蟒/扩张的反应(使用压力myography),同时采用膜片钳电生理技术)可以揭示有关的重要信息的的KV7渠道作用在血管平滑肌生理和药理学。

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