Journal
/
의학
/
清醒小鼠滴鼻的CNS药物治疗管理
JoVE 신문
의학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 의학
Intranasal Administration of CNS Therapeutics to Awake Mice
Please note that all translations are automatically generated. Click here for the English version.

清醒小鼠滴鼻的CNS药物治疗管理

DOI:
10.3791/4440-v

•

07:15 min

•

April 08, 2013

•

, , ,
1Alzheimer’s Research Center at Region’s Hospital,HealthPartners Institute for Education and Research

Chapters

  • 00:05Title
  • 01:20Acclimation to Handling for Intranasal Dosing to Awake Mice
  • 04:15Intranasal Delivery of Drug to Awake Mice
  • 05:57General Animal Handling Techniques for Acclimation and Intranasal Delivery of Drug to Awake Mice
  • 06:34Conclusion

Summary

자동 번역

자동 번역

目的针对脑清醒小鼠鼻内给药的方法，进行说明。这种方法允许重复给药，长期使用鼻腔给药的药物无需麻醉，并以最小的全身暴露的鼻子到大脑传递。

Tags

Intranasal AdministrationCNS TherapeuticsAwake MiceNon-invasive DeliveryBlood-brain BarrierTargeted Drug DeliverySystemic ExposureIntranasal Delivery In Clinical TrialsPharmacokinetic DistributionEfficacy EvaluationAwake Delivery In MiceChronic Dosing Without AnesthesiaIntranasal Grip For Mice

Article

Embed

플레이리스트에 추가

Usage Statistics

Related Videos

check_url/kr/4440?article_type=v

允许有针对性的大鼠模型血 - 脑屏障破坏神经血管治疗
check_url/kr/4440?article_type=v

一种新型的高分辨率<em>在体内</em>成像技术研究肿瘤生长及治疗颅内结构的动态响应
check_url/kr/4440?article_type=v

颈动脉输液的紫杉烷类化合物在小鼠体内的药代动力学和药效学分析
check_url/kr/4440?article_type=v

新的治疗肠道病变的疗效，使用活体小鼠的串行内镜成像的非侵入性评估
check_url/kr/4440?article_type=v

大鼠颈动脉球囊损伤模型试验抗血管重建治疗
check_url/kr/4440?article_type=v

透过玻璃看：时间推移显微镜和单细胞的纵向跟踪研究抗癌治疗
check_url/kr/4440?article_type=v

纵<em>在体内</em>的Cerebrovasculature影像：相关性疾病CNS
check_url/kr/4440?article_type=v

评估在鼠标模型中执行唤醒膀胱测压的过程
check_url/kr/4440?article_type=v

在小鼠模型中将胶质母细胞瘤治疗干细胞的鼻内递送
check_url/kr/4440?article_type=v

吸入麻醉下鼻内给药评价鼻腔给脑药物的新方法

Read Article