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啮齿动物的中枢神经系统药物直接脑室交货
JoVE 신문
신경과학
This content is Free Access.
JoVE 신문 신경과학
Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System
DOI:

14:55 min

May 12, 2013

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Chapters

  • 00:05Title
  • 01:54Pre-Surgical Procedure
  • 03:49Implantation of Alzet Osmotic Pump
  • 08:01Changing or Removing Alzet Osmotic Pump
  • 09:51Administration of an Intracerebroventricular Bolus
  • 12:12Results: Intraventricular Delivery of Antisense Oligonucleotides to the Rodent Central Nervous System
  • 14:36Conclusion

Summary

자동 번역

我们描述了一种方法,目标通过植入导管或进行大剂量注射到在小鼠右侧脑室中枢神经系统的药物。我们特别专注于交付反义寡核苷酸。这种技术是很容易适应其他药物和大鼠。

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