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Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
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Chapters
- 00:05Title
- 01:16Preparation of Viral Suspension
- 02:14Injection of Neonates
- 03:25In vivo Imaging
- 05:00Results: Viral Expression Over Time
- 05:32Conclusion
Human Cytomegalovirus (HCMV) infection of neonates represents an important cause of mental retardation, yet the molecular events leading to virus-induced pathogenesis are still poorly understood. To investigate the dynamics of brain infection, we adapted whole-animal in vivo imaging to perform time-course analysis of neonates infected with a luciferase-recombinant virus.
