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Bioengineering

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JoVE Journal Bioengineering
Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
 

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Article DOI: 10.3791/50438-v • 12:20 min • July 22nd, 2013
July 22nd, 2013 •
1, 1
1Department of Electrical Engineering and Computer Science, University of Michigan - Ann Arbor

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We describe the device fabrication and measurement protocol for carbon nanotube based high frequency biosensors. The high frequency sensing technique mitigates the fundamental ionic (Debye) screening effect and allows nanotube biosensor to be operated in high ionic strength solutions where conventional electronic biosensors fail. Our technology provides a unique platform for point-of-care (POC) electronic biosensors operating in physiologically relevant conditions.

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Keywords: Carbon Nanotubes Nanoelectronic Biosensor High Frequency High Ionic Strength Electrical Double Layer Charge Screening Frequency Mixing Single-walled Carbon Nanotubes Semiconductor Nanowires Field Effect Transistors Transconductance PDMS Microfluidics
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