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1Department of Pharmaceutical Sciences,University of Toronto, 2The Institute of Biomaterials and Biomedical Engineering,University of Toronto, 3Ontario Cancer Institute,Campbell Family Institute For Cancer Research and Techna Institute, 4Department of Biomedical Engineering,University at Buffalo, The State University of New York
Chapters
- 00:05Title
- 01:41Preparation of Porphysomes
- 05:27In vivo Photothermal Therapy
- 07:43Porphysome Characterization and Tumor Treatment Results
- 09:23Conclusion
Desarrollamos nuevos nanovesículas multifuncionales intrínsecas llamados porphysomes, que tienen la estructura dependiente de fluorescencia propiedades fototérmicos únicas de auto-extinción y, por lo que funciona agentes de terapia fototérmica como potentes. Formulamos porphysomes por extrusión a alta presión y se investigó su eficacia de la terapia fototérmica en un modelo de tumor de xenotrasplante.
Tags
PorphysomesPhotothermal Tumor AblationIntrinsic Multifunctional NanovesiclesPhotosensitizerPyropheophorbide αPhospholipidLiposome-like Spherical VesiclesExtinction CoefficientsFluorescence Self-quenchingPhotothermal EfficacyHigh Pressure ExtrusionTumor Temperature IncreaseLaser IrradiationThermal AblationEscharsPhotothermal Therapy (PTT)
