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在收缩力测量评估肌肉功能在斑马鱼幼虫
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JoVE 신문 생물학
Force Measurement During Contraction to Assess Muscle Function in Zebrafish Larvae
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在收缩力测量评估肌肉功能在斑马鱼幼虫

DOI:
10.3791/50539-v

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08:25 min

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July 23, 2013

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, , ,
1Department of Biomedical Engineering,University of Michigan , 2Department of Surgery, Section of Plastic Surgery,University of Michigan , 3Departments of Pediatrics and Neurology,University of Michigan , 4Department of Molecular and Integrative Physiology,University of Michigan

Chapters

  • 00:05Title
  • 01:12Preparing Suture Loops
  • 01:50Preparing the Experimental Chamber and Positioning the Larva
  • 04:11Recording Force During a Maximal Twitch Contraction
  • 06:20Measuring Musculature Dimensions with Larva at Optimal Length
  • 07:00Results: Peak Force During Maximal Twitch
  • 07:56Conclusion

Summary

자동 번역

자동 번역

力的测量可以用来演示肌肉功能的变化，由于开发，损伤，疾病，治疗或化学毒性。在这段视频中，我们展示了一个方法来测量期间最大的斑马鱼幼体躯干肌肉收缩力。

Tags

Force MeasurementMuscle FunctionZebrafish LarvaeMuscle ContractionIsometric TwitchForce TransducerLength ControllerElectric Field StimulationMuscle DevelopmentMuscle DiseaseMuscle Toxicity

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