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JoVE Journal Neuroscience
Funktionel Interrogation Adult Hypothalamus Neurogenese med Focal Radiological Hæmning
 
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Funktionel Interrogation Adult Hypothalamus Neurogenese med Focal Radiological Hæmning

Article DOI: 10.3791/50716-v • 11:45 min • November 14th, 2013
November 14th, 2013 •
1,2, 2, 3, 3, 4, 2,5
1Division of Biology, California Institute of Technology, 2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology, Johns Hopkins University School of Medicine, 3Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, 4Department of Radiation Oncology, University Of Washington Medical Center, 5Institute for Cell Engineering and High-Throughput Biology Center, Johns Hopkins University School of Medicine

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Funktionen af ​​pattedyr neuroner voksen-fødte er fortsat et aktivt område af undersøgelsen. Ioniserende stråling hæmmer fødslen af ​​nye neuroner. Ved hjælp af computer tomografi-guidede omdrejningspunkt bestråling (CFIR), kan tre-dimensionelle anatomisk målretning af specifikke neurale progenitorpopulationer nu bruges til at vurdere den funktionelle rolle af voksne neurogenese.

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Neuroscience neurale stamceller (NSC) kropsvægt strålebehandling Image-Guided Metabolism energiomsætning Neurogenese celleproliferation Neurosciences bestråling Radiologisk behandling Computer-tomografi (CT) Hypothalamus Hypothalamus proliferativ Zone (HPZ) Median Eminence (ME) Small Animal Radiation Research Platform (SARRP)
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