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原正畸胶质血异草回顾渗透生长和同源脱氢酶 I 突变

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Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation

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原正畸胶质血异草回顾渗透生长和同源脱氢酶 I 突变

DOI:

10.3791/50865-v

•

09:43 min

•

January 14, 2014

•

J. Geraldo Valadez, Anuraag Sarangi, Christopher J. Lundberg, Michael K. Cooper^2,3

¹Department of Neurology,Vanderbilt University Medical Center, ²Vanderbilt Ingram Cancer Center,Vanderbilt University Medical Center, ³Neurology Service,Veteran Affairs TVHS

Chapters

00:05Title
01:49Preparation of Tumor Cell Suspension
04:41Intracranial Transplantation
06:22Tumor Harvesting
07:25Results: Tumor Growth after Grafting
09:15Conclusion

Summary

자동 번역

恶性胶质瘤是一组具有明显临床和分子特征的高度渗透性胶质肿瘤的异质性群体。原位矫形异种格拉夫特在前科动物模型中重新概括恶性胶质瘤亚型的组织病理学和分子特征。

Tags

Glioma Xenograft Orthotopic Infiltrative Growth Isocitrate Dehydrogenase Malignant Glioma WHO Grade III WHO Grade IV Primary Xenograft Tumor Transplantation Immunocompromised Mice Tumor Dissociation Surgical Procedure

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