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Inductie van Invasieve Transitional Cell blaascarcinoom in Immune Intact Human MUC1 transgene muizen: Een model voor Immunotherapie Ontwikkeling
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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
DOI:

11:02 min

October 30, 2013

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Chapters

  • 00:05Title
  • 01:43Bladder Cancer Induction and Vaccination Treatments
  • 02:49Monitoring and Sample Collection
  • 04:11Multiplex Fluorometric Microbead Immunoassay
  • 06:37IFN-γ/IL-4 ELISpot Preparation and Analysis
  • 08:07Representative Transitional Cell Bladder Carcinoma Induction Results
  • 10:39Conclusion

Summary

자동 번역

Een N-butyl-N-(4-hydroxybutyl) nitrosamine-geïnduceerde blaaskanker model werd ontwikkeld in humane mucine 1 (MUC1) transgene muizen voor de beproeving van de MUC1-gerichte immunotherapie. Na toediening van een MUC1-gericht peptide vaccin was een cytotoxische T-lymfocyt respons tegen MUC1 bevestigd door metingen van serum cytokinen en T-cel-specifieke activiteit.

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