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Chapters
- 00:05Title
- 01:44In vivo Analysis of Skeletal Muscle Structure by Birefringence
- 04:23Touch-evoked Escape Behavior Assay
- 05:10Results: Representative WT and Mutant Skeletal Muscle Analyses
- 07:28Conclusion
The zebrafish is now an established and powerful tool for modeling muscular dystrophies, congenital myopathies, and related neuromuscular diseases. Birefringence and touch-evoked escape behavior are two common noninvasive assays used to determine the degree of muscular disorganization and locomotive impairment of zebrafish embryos during early development.
