This content is Free Access.
1Division of Hematology-Oncology, Department of Internal Medicine,University of Cincinnati College of Medicine, 2Division of Human Genetics,University of Cincinnati College of Medicine, 3Department of Radiology,University of Cincinnati College of Medicine, 4Division of Rheumatology, Cincinnati Children’s Hospital Medical Center,University of Cincinnati College of Medicine, 5Solid Tumor Biology Program, James Comprehensive Cancer Center,The Ohio State University Medical Center, 6Department of Neurological Surgery, James Comprehensive Cancer Center,The Ohio State University Medical Center
Chapters
- 00:05Title
- 01:25Preparation of Animal Models and Fluorescently-labeled SapC-DOPS Nanovesicles
- 03:27Fluorescence Imaging
- 05:30Results: Optical Imaging of Brain Tumors and Arthritis in SapC-DOPS Nanovesicle Injected Mice
- 08:35Conculsion
Descreve-se um sistema (Maroi) para in vivo quantificação de um marcador fluorescente entregue por saposina C (SAPC)-dioleoylphosphatidylserine (DOPS) nanovesículas multi-ângulo de rotação de imagem óptica. Utilizando modelos de ratinho de cancro e artrite, é mostrado como a análise da curva de sinal Maroi pode ser utilizado para o mapeamento preciso e caracterização biológica de processos de doença.
