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A Murine Model of Cervical Spinal Cord Injury to Study Post-lesional Respiratory Neuroplasticity
 

A Murine Model of Cervical Spinal Cord Injury to Study Post-lesional Respiratory Neuroplasticity

Article DOI: 10.3791/51235-v • 09:09 min • May 28th, 2014
May 28th, 2014 •
1, 1, 1,2, 1,2, 1,3, 1
1UFR des sciences de la santé - Simone Veil, Université de Versailles Saint-Quentin-en-Yvelines, 2Service de Physiologie - Explorations fonctionnelles, Hôpital Ambroise Paré, 3Services de Physiologie, Explorations Fonctionnelles, Réanimation Médicale et Centre d'Investigation Clinique et d'Innovation Technologique (Unité Inserm 805), Université de Versailles Saint-Quentin-en-Yvelines

챕터

요약
Automatic Translation

Respiratory failure is the leading cause of death following a cervical spinal cord injury. Having a reproducible, quantifiable, and reliable pre-clinical animal model of respiratory failure induced by a partial cervical injury will help to understand the subsequent respiratory and non-respiratory neuroplasticity and allow testing putative repair strategies.

Tags

Keywords: Murine Model Cervical Spinal Cord Injury Respiratory Neuroplasticity Pre-clinical Model C2 Level Injury Diaphragm Paralysis Phrenic Nerve Respiratory Function Respiratory Neuroplasticity Therapeutic Strategies Respiratory Failure
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