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Chapters
- 00:05Title
- 01:58Preparations for Surgery
- 02:54The Collagenase Injection Model
- 04:54The Autologous Blood Injection Model
- 06:48Post-operative Care
- 07:25Hematoma Formation and Neurological Deficits of Injured Mice
- 08:39Conclusion
Preclinical models of intracerebral hemorrhage are utilized to mimic certain aspects of clinical disease. Thus, mechanisms of injury and potential therapeutic strategies may be explored. In this protocol, two models of intracerebral hemorrhage are described, intrastriatal (basal ganglia) injections of autologous blood or collagenase.
