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Modellering Stroke i mus: Permanent Koagulering af den distale Middle Cerebral Artery
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Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

Modellering Stroke i mus: Permanent Koagulering af den distale Middle Cerebral Artery

DOI:
10.3791/51729-v

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08:14 min

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July 31, 2014

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, , , ,
1Institute for Stroke and Dementia Research,University Hospital Munich, 2Munich Cluster for Systems Neurology (SyNergy), 3Department of Neurology,University Heidelberg, 4Imperial College,Charing Cross Hospital

Chapters

  • 00:05Title
  • 01:38Preparations
  • 02:32The Distal MCAO Model
  • 04:52The Cylinder Test
  • 05:45Measuring the Infarction
  • 06:31Mortality, Behavioral Change, and Infarct Characterization
  • 07:30Conclusion

Summary

자동 번역

자동 번역

Forskellige murine modeller af midterste cerebral arterie okklusion (MCAO) er meget udbredt i eksperimentel hjerneforskning. Her demonstrerer vi den model af transkraniel permanent distale MCAO der producerer konsekvent kortikal infarkt af en størrelse svarende til skade pålagt af flertallet af de menneskelige iskæmisk slagtilfælde.

Tags

StrokeMouse ModelMiddle Cerebral ArteryCoagulationInfarctPermanent OcclusionCortexReproducibilityLow MortalityPathophysiologyInflammationAngiogenesisPlasticityRegenerationTherapeutic Strategies

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