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让合规的强制锻炼鼠害:一项关键的标准在衰老相关的疾病和疾病评估运动的影响
JoVE 신문
행동분석학
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JoVE 신문 행동분석학
Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
DOI:

10:19 min

August 22, 2014

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Chapters

  • 00:05Title
  • 02:01Baseline Locomotor Activity Assessments: Determining Forced Exercise Group Assignments
  • 04:08Acclimation on the Treadmill
  • 06:32Treadmill Exercise Training
  • 07:36Representative Results: Evaluation of Baseline Locomotor Activity, Treadmill Exercise Scores, and Body Weight
  • 09:17Conclusion

Summary

자동 번역

Exercise may alleviate behavioral impairments associated with neurodegenerative diseases. Studies of the mechanisms underlying exercise-mediated effects have increased in disease models, but the neurobiological background accompanying these diseases, specifically aging, is likely not considered. Here, we illustrate measures to increase the likelihood of a successful exercise paradigm in aged rats.

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