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Neuroscience

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JoVE Journal Neuroscience
Real-time beeldvorming van Axonale Vervoer van Quantum Dot-label BDNF in primaire neuronen
 
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Real-time beeldvorming van Axonale Vervoer van Quantum Dot-label BDNF in primaire neuronen

Article DOI: 10.3791/51899-v • 10:53 min • September 15th, 2014
September 15th, 2014 •
1, 2, 1, 3,4, 1, 1
1Department of Neurosciences, University of California, San Diego, 2School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 3Department of Anesthesiology, University of California, San Diego, 4VA San Diego Healthcare System

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Axonale transport van BDNF, een neurotrofe factor, is van cruciaal belang voor de overleving en functie van verschillende neuronale populaties. Sommige degeneratieve stoornissen worden gekenmerkt door verstoring van axonale structuur en functie. We toonden de technieken die gebruikt worden om live handel in QD-BDNF in microfluïdische kamers met zowel primaire neuronen te onderzoeken.

Tags

Neurowetenschappen live imaging brain-derived neurotrophic factor (BDNF) quantum dot mensenhandel axonale retrograde transport microfluïdische kamer
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