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Chapters
- 00:05Title
- 01:32Equipment Preparation
- 02:32Cell Preparation
- 03:19Surgical Preparation
- 04:10Intracranial Injection
- 08:10Recovery & Tumor Development
- 08:55Results: Tumor Growth After Intracranial Injection
- 10:31Conclusion
The brain is a unique site with qualities that are not well represented by in vitro or ectopic analyses. Orthotopic mouse models with reproducible location and growth characteristics can be reliably created with intracranial injections using a stereotaxic fixation instrument and a low pressure syringe pump.
