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Porous Silicon Microparticles for Delivery of siRNA Therapeutics
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JoVE 신문 생체공학
Porous Silicon Microparticles for Delivery of siRNA Therapeutics
DOI:

08:31 min

January 15, 2015

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Chapters

  • 00:05Title
  • 00:58PCPS Particle Preparation
  • 03:46PCPS Particle Characterization
  • 04:33Loading of siRNA into PCPS Particles and Optimization of siRNA/PCPS Particle Ratio
  • 05:31Release of siRNA from PCPS Particles
  • 06:16Results: Characterization of Porous Silicon Microparticles for siRNA Delivery
  • 08:02Conclusion

Summary

자동 번역

Delivery remains the main challenge for the therapeutic implementation of small interfering RNA (siRNA). This protocol involves the use of a multifunctional and biocompatible siRNA delivery platform, consisting of arginine and polyethylenimine grafted porous silicon microparticles.

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