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Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice
JoVE 신문
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Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice
DOI:

09:05 min

May 04, 2015

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Chapters

  • 00:05Title
  • 01:19Intubation
  • 02:34Myocardial Infarction Induction
  • 04:13Suture and Recovery
  • 04:57Myocardial Infarction Analysis
  • 06:50Results: Representative Myocardial Infarction Analyses
  • 08:29Conclusion

Summary

자동 번역

A highly reproducible model for myocardial infarction in mice with minimal invasive manipulations is described. The model can be easily performed, resulting in a high reproducibility and survival rate. Thus, the described model will reduce the number of required animals as requested by the 3R principle (Replacement, Refinement and Reduction).

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