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JoVE Journal Medicine
Metod för Isolerad
 
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Metod för Isolerad

Article DOI: 10.3791/52309-v • 08:59 min • February 25th, 2015
February 25th, 2015 •
1,2, 1,2, 3, 4, 2, 5,6, 3,7, *1,2,3, *2,3,4
1Department of Biomedical Engineering, Ohio State University Wexner Medical Center, 2Davis Heart & Lung Research Institute, Ohio State University Wexner Medical Center, 3The Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Laboratory, Ohio State University Wexner Medical Center, 4Division of Cardiac Surgery, Department of Surgery, Ohio State University Wexner Medical Center, 5Departments of Pediatrics and Internal Medicine, Ohio State University, 6Advanced Lung Disease Program, Lung and Heart-Lung Transplant Programs, Nationwide Children's Hospital, 7Division of Transplantation, Department of Surgery, Ohio State University Wexner Medical Center
* These authors contributed equally

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요약
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Ex-vivo Lung Perfusion (EVLP) har tillåtit lungtransplantation hos människor att bli mer lättillgängliga genom att förmågan att bedöma organ och expandera donatorpool. Här beskriver vi utvecklingen av en råtta EVLP programmet och förfiningar som möjliggör en reproducerbar modell för framtida expansion.

Tags

Medicin EVLP VILI tidalvolym PEEP lungtransplantation övertrycksventilation
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