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Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
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Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa

DOI:
10.3791/52927-v

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07:46 min

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October 22, 2015

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, ,
1Center for Neural Science,New York University

Chapters

  • 00:05Title
  • 01:39Preparations
  • 02:47Acclimation Phase
  • 03:39Food Restriction Phase
  • 04:54Ending the Experiment
  • 05:51Approximating ABA in Pubescent Female Mice
  • 06:42Conclusion

Summary

자동 번역

자동 번역

Here we present a protocol to induce activity-based anorexia (ABA) in female adolescent mice. ABA is a condition of hyperactivity evoked by imposing food restriction on rodents with access to a running wheel. This phenomenon is being used as a model to study the underlying neurobiology of anorexia nervosa.

Tags

Keywords: Activity-based AnorexiaAnorexia NervosaRodent ModelNeurobiologyHyperactivityFood RestrictionRunning WheelCircadian RhythmC57BL/6 Mice

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