Journal
/
의학
/
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
JoVE 신문
의학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 의학
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

DOI:
10.3791/52978-v

•

06:01 min

•

August 18, 2015

•

,
1Department of Pediatrics, Division of Neurology,The Emory University School of Medicine

Chapters

  • 00:05Title
  • 01:40Transient Cerebral Hypoxia-ischemia
  • 03:54Laser Speckle Contrast Imaging (LSCI)
  • 04:43Tissue Plasminogen Activator (tPA) Administration and Brian Damage Detection
  • 05:28Conclusion

Summary

자동 번역

자동 번역

Thromboembolic stroke models are vital tools for optimizing the recanalization therapy. Here we report a murine thrombotic stroke model based on transient cerebral hypoxic-ischemic (tHI) insult, which triggers thrombosis and infarction, and responds favorably to tissue plasminogen activator (tPA)-mediated fibrinolysis in a therapeutic window similar to those in stroke patients.

Tags

Keywords: Thrombotic Stroke ModelTransient Cerebral Hypoxia-ischemiaTPAReperfusion DeficitsFibrin And Platelet DepositionMiddle Cerebral ArteryPreclinical Stroke Research

Article

Embed

플레이리스트에 추가

Usage Statistics

Related Videos

check_url/kr/52978?article_type=v

Modeling Stroke in Mice – Middle Cerebral Artery Occlusion with the Filament Model
check_url/kr/52978?article_type=v

Intraluminal Middle Cerebral Artery Occlusion (MCAO) Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Mice
check_url/kr/52978?article_type=v

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
check_url/kr/52978?article_type=v

Endothelin-1 Induced Middle Cerebral Artery Occlusion Model for Ischemic Stroke with Laser Doppler Flowmetry Guidance in Rat
check_url/kr/52978?article_type=v

Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
check_url/kr/52978?article_type=v

A Murine Model of Subarachnoid Hemorrhage
check_url/kr/52978?article_type=v

Excitotoxic Stimulation of Brain Microslices as an In vitro Model of Stroke
check_url/kr/52978?article_type=v

Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery
check_url/kr/52978?article_type=v

Embolic Middle Cerebral Artery Occlusion (MCAO) for Ischemic Stroke with Homologous Blood Clots in Rats
check_url/kr/52978?article_type=v

Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia

Read Article