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Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
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Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

DOI:
10.3791/53181-v

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09:49 min

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August 13, 2015

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, , ,
1Anatomy and Cell Biology,University of Kansas Medical Center

Chapters

  • 00:05Title
  • 01:56Neonatal Maternal Separation
  • 03:48Perigenital Mechanical Sensitivity Assessment
  • 05:20Staining Prostate Cryosections for Identification of Mast Cells
  • 08:10Results: Neonatal Maternal Separated Mice Display Evidence of Chronic Prostatitis / Chronic Pelvic Pain Syndrome
  • 09:01Conclusion

Summary

자동 번역

자동 번역

We are measuring perigenital mechanical sensitivity and mast cell activation in the prostate of male C57BL/6 mice that underwent an early life stress paradigm – neonatal maternal separation, in order to induce a preclinical model of chronic prostatitis/chronic pelvic pain syndrome.

Tags

Keywords: Neonatal Maternal SeparationChronic ProstatitisChronic Pelvic Pain SyndromeCP/CPPSHypothalamic-pituitary-adrenal AxisMast Cell ActivationPerigenital SensitivityPreclinical ModelC57BL/6 Mice

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