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Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
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Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

DOI:
10.3791/53191-v

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07:21 min

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September 28, 2015

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, , , , , ,
1Saha Cardiovascular Research Center,University of Kentucky, 2Department of Pharmacology and Nutritional Sciences,University of Kentucky

Chapters

  • 00:05Title
  • 00:59Osmotic Pump Filling
  • 03:45Pump Implantation
  • 05:45Results: Aortic Images from Mice Infused with AngII
  • 07:01Conclusion

Summary

자동 번역

자동 번역

Subcutaneous implantation of osmotic pumps provides a convenient approach for prolonged and consistent delivery of compounds. This approach has been used extensively to study both abdominal and thoracic aortic aneurysms in mice.

Tags

Keywords: Subcutaneous InfusionAngiotensin IIOsmotic PumpsAortic AneurysmsMiceHypercholesterolemiaGender DependenceAbdominal Aortic AneurysmsThoracic Aortic Aneurysms

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