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Turbativa Anti-virulento di patogeni biofilm utilizzando Engineered Quorum-tempra Lactonases
JoVE 신문
면역학 및 감염병학
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JoVE 신문 면역학 및 감염병학
Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
DOI:

07:47 min

January 01, 2016

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Chapters

  • 00:05Title
  • 00:44Crystal Violet Quantitation of Biofilm Formation in A. baumannii S1
  • 02:48Confocal Laser Scanning Microscopy A. baumannii S1 Biofilms
  • 05:00Results: Pathogenic Biofilm Disruption
  • 06:28Conclusion

Summary

자동 번역

Quorum-quenching enzymes are anti-virulent and anti-bacterial options that can mitigate pathogenesis without risk of incurring resistance, by preventing the expression of virulence factors and genes associated with antibiotic resistance and biofilm formation. In this study, we report a method that demonstrates the efficacy of quorum-quenching enzymes in bacterial biofilm disruption.

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