October 7th, 2015
This study describes an accurate, reliable and non-invasive technique to continuously measure gastrointestinal temperature during exercise. The ingestible telemetric temperature pill is suitable to measure gastrointestinal temperature in laboratory settings as well as in field based settings.
The overall goal of this procedure is to get an accurate and reliable measurement of the gastrointestinal temperature during exercise using an ingestible telemetric temperature pill in lab-based as well as field-based conditions. This is accomplished by first ensuring that all the subjects do not meet the exclusion criteria and then instructing them in how to correctly use the temperature pill. The second step is to choose the right measurement protocol and to import the temperature pill, serial numbers into the recorder, as well as set the desired frequency protocol measurement unit and calibration numbers.
Next, the data collection is started and the gastrointestinal temperature is measured throughout the entire protocol. The final step is to extract the data from the external recorder and visually check the data for missing values and outliers. Ultimately, changes in gastrointestinal temperature are accurately tracked over time and can be compared with temporal or other protocol-based data.
The main advantage of this technique over existing methods like the esophageal rectal and typa temperature measurement, is that the gastrointestinal temperature measurement using a telemetric temperature pill is less invasive, more accurate, and easily applicable in both lab and field-based conditions. To begin, speak to each of the study subjects and instruct them to ingest the temperature pill with a glass of water at least six hours prior to the scheduled start of the experiment. This will avoid any interaction with fluid ingestion.
Show the subjects how to remove the magnetic strip from the pill and instruct them to do so prior to ingestion. This will activate the battery and enable measuring. Then ask the subjects to return the pill wrapping material to the research team once the pill is ingested so they can check serial and calibration numbers prior to the start of the experiment.
Inform the subjects that the temperature pill will leave the body through its natural way in the feces and that it can be flushed through the toilet. Using the cross-sectional mode, make it possible to measure up to 99 subjects simultaneously Prior to the cross-sectional measurement. Adjust the recorder settings by first turning on the recorder.
Then connect the recorder with the computer with the transfer cable, and to push the F1 PC link button to enable the recorder to connect with the computer, open the software supplied by the device's manufacturer and click on program in the home screen. Then select the open PC link button to make a connection with the recorder. Select the cross sectional measurement mode by selecting sports mode on.
Also select the correct temperature measurement scale, and then select the right config to recorder button to copy the settings to the recorder. Next, push the sensor barcode display button, and then the right sensors to recorder button to add all the serial and calibration numbers of all the individual subjects to the external recorder. Check the battery of the recorder prior to each measurement.
A battery state of 75%is normally sufficient to measure for at least 24 hours. Once all preparations are completed and the predefined settings are checked, start the experiment by detaching the recorder returning to the home screen and using the F two sport button to start data acquisition. When player zero one appears on the screen, push the read button to measure gastrointestinal temperature.
Press the read button again for an extra measurement to switch users. Push on the correct number on the recorder, and subsequently measure the core body temperature by pushing the read button. Stop the data collection by pushing the stop button.
When the measurement is finished, turn off the recorder by first pressing the enter button, followed by the exit button. When turn off recorder appears, use the power switch to turn off the recorder. The continuous mode of the recorder enables one to measure and save the gastrointestinal temperature of an individual subject continuously over a predefined interval.
Once the recorder has been connected to the computer as previously shown, select the continuous measurement mode by selecting sports mode off. Then select a measuring frequency by adjusting the read interval to the right constant time interval with a minimal sampling interval of 10 seconds. Also, select the correct temperature measurement scale as before, and then use the right config to recorder button to copy the settings to the recorder.
Next, push the sensor barcode display button, and then the right sensors to recorder button to add the serial and calibration numbers of the individual subject to the external recorder. Check the battery of the recorder prior to the experiment. When measuring in continuous mode, a battery state of 75%is sufficient to perform a 24 hour measurement.
Once all preparations are complete and the predefined settings are checked, detach the recorder and start the experiment by pushing the run button on the home screen of the recorder With the recorder activated. Place it in a waste bag of the subject so that it is less than 30 to 40 centimeters from their abdomen. In order to avoid measurement errors when the experiment is over, stop the measurements by pushing the stop button.
Use the F1 exit button to get the turn off unit, and then use the power switch to turn off the recorder, connect the recorder to the computer and then open the software and click the download button on the home screen. Enter a file name and push the okay button to store the data as a CVT file, which can be opened using spreadsheet software. Next, open the data file and visually check the collected data for missing data and outliers.
A decrease or increase of the gastrointestinal temperature by more than one degree in less than one minute is very unrealistic and can be caused by disturbances of the radio signal. As a result, the unrealistic data point can be removed for further analysis. Finally, interpolate the missing values by averaging the previous and next valid value.
After obtaining baseline temperatures before subjects shown here walked 30 kilometers at a self-selected pace during exercise, the gastrointestinal temperature was measured every five kilometers as well as directly after finishing the 30 kilometer walk. The figure demonstrates that the cross-sectional mode enables measurement of a group of subjects using the same equipment. The temperature pill can also be used to perform continuous gastrointestinal temperature measurements in which the temperature is measured continuously at a high temporal resolution.
In the example presented here, the gastrointestinal temperature of four healthy adults were measured every minute for 24 hours and average to assess the circadian rhythm of the gastrointestinal temperature. After watching this video, you should have a good understanding of how to measure the gastrointestinal temperature during lab and field-based settings using an ingestible telemetric temperature bill.
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Deze studie beschrijft een niet-invasieve techniek om de gastro-intestinale temperatuur tijdens inspanning te meten met behulp van een inslikbare telemetrische temperatuurpil. Deze methode is geschikt voor zowel laboratorium- als veldcondities.