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Bioengineering

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Easy and Accurate Mechano-profiling on Micropost Arrays
 

Easy and Accurate Mechano-profiling on Micropost Arrays

Article DOI: 10.3791/53350-v 10:25 min November 17th, 2015
November 17th, 2015

챕터

요약

Described are protocols for quantifying mechanical interactions between adherent cells and microstructured substrates. These interactions are closely linked to essential cell behaviors including migration, proliferation, differentiation, and apoptosis. The protocols present an open-source image analysis software called MechProfiler, which enables determination of involved forces for each micropost.

Tags

Keywords: Micropost Arrays Cell-substrate Interactions Traction Force Microscopy Mechano-profiling Cell Phenotypes Bone Cancer Cells Metastasis Commercial Traction Force Sensors Open Source Software Non-expert Users
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