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Chapters
- 00:05Title
- 01:03White Matter Stroke Induction: Medial Angled Approach
- 05:12Tissue Processing for Protein or RNA Analysis
- 06:47Results: Focal White Matter Stroke Using Both Medial and Posterior Angled Approach
- 08:02Conclusion
Here we present methodology for the production of a focal stroke in murine white matter by local injection of an irreversible endothelial nitric oxide synthase (eNOS) inhibitor (L-Nio). Presented are two stereotactic variations, retrograde neuronal tracing, and fresh tissue labeling and dissection that expand the potential applications of this technique.
