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弥漫性光学光谱治疗急性电离辐射引起的皮肤毒性的定量评价使用小鼠模型
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Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
DOI:

06:21 min

May 27, 2016

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Chapters

  • 00:05Title
  • 00:46Diffuse Optical Spectroscopy (DOS) Data Acquisition: Preparations
  • 01:55Taking DOS Measurements from an Anesthetized Mouse
  • 03:01Mouse Irradiation
  • 04:32Results: DOS and Traditional Measurements
  • 05:36Conclusion

Summary

자동 번역

We present a diffuse optical spectroscopic (DOS) approach that provides quantitative optical biomarkers of skin response to radiation. We describe DOS instrumentation design, optical parameters extraction algorithms and the animal handling procedures required to yield representative data from a pre-clinical mouse model of radiation induced erythema.

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