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Chapters
- 00:05Title
- 00:48Bioluminescence Imaging
- 02:40Bioluminescence Quantification and Image Analysis
- 03:59Results: Representative Tumor Burden Monitoring and Treatment Response in Various Mouse Lymphoma Models
- 06:10Conclusion
Bioluminescence imaging is a well-known tool for localizing tumors and metastases, but quantification of these images often requires complex calculations and particular instruments. We describe the easy-to-use luminoscore method, based on precise acquisition conditions, requiring no calculations, and enabling tumor burden and treatment response to be monitored in mouse models.
Tags
Bioluminescence-based Tumor Quantification MethodMonitoring Tumor ProgressionTreatment EffectsMouse Lymphoma ModelsBioluminescence Acquisition ProceduresImage AnalysesQuantitative DataReproducible Quantification Of Imaging DataAdvantages Of The TechniqueEasy Setup In Any Animal FacilityDoes Not Require Complex CalculationsImager InitializationSedation Level ConfirmationD-Luciferin Potassium Salt Solution InjectionFirefly Luciferase Expression In Tumor CellsLight Production And Detection With The ImagerImaging Of Posterior And Anterior Body Positions
