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Chapters
- 00:05Title
- 00:53Optimization of Emulsion Conditions
- 03:21Preparation of Dacarbazine-loaded NLC
- 04:35Results: Encapsulation of Dacarbazine Using NLC to Improve Therapeutic Profiling
- 05:59Conclusion
The most commonly used method for nanostructured lipid carrier (NLC) synthesis involves oil-in-water emulsion, homogenization and solidification. This was modified here by applying high shear dispersion after solidification to achieve a NLC with desirable size, improved drug encapsulation and drug loading efficiency as a potential carrier for dacarbazine delivery.
